It is widely believed
that IMSI used in IVF is a better technique
than ICSI though this claim is yet to be backed by rational evidence.
The smallest cell in the
human body; a sperm from the male and the largest; an egg from the female,
unite to fuse their genetic material together and create a new being. There
are approximately 20 – 150 million sperms in a normal human semen ejaculate,
often with dissimilar appearances. Diversely structures and shapes of human
sperms clearly stand out against most animal sperms which are perfectly
shaped. At Malpani fertility clinic, to examine a sperm sample we
stain the sperms and observe them under a microscope at high magnification to
study their shapes. Researchers investigating male fertility were particularly
curious to know whether the sperm’s shape would affect male fertility, leading
to several studies intending to find out what a normal human sperm actually
looked like.
Animals have identical looking
sperms which makes it easy to distinguish abnormally shaped sperms. But reviews of several studies suggest that
sperms in a human semen sample have a wide range of variability in their
morphology, in a single ejaculate, several ejaculates from the same fertile
male and those from other fertile males. It is, therefore, difficult to define
the normal morphology of human sperm. With such high variability in the shape
of the human sperm even from fertile males it is hard to comment on which sperm
is abnormally shaped and which is not. Thus, sperm morphology cannot be used to
gauge the fertility potential of men. To know how this impacts the debate of
IMSI vs. ICSI read http://blog.drmalpani.com/2012/12/is-imsi-better-than-icsi.html
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